In general immediately after burn, the wound was in aseptic state but the wound was infected. While the delay and control of burn wound infection was possible, it was difficult to keep the wound perfectly aseptic until complete healing.
I studied thirty admitted patients, within six hours after burn, who had the extent of burns less than 70% of body surface area.
Cultures of local wound discharge in postburn 5th, 7th and 9th. day in reach cases were performed for the observation of the rate of bacterial infection, kinds of bacteria, periodic change and susceptibility to antibiotics.
Acquired results were as follows.
1. Positive in 63 cases (70%), and negative in 27 cases (30%) in a total of 90 cases.
2. A single bacillus was identified in 44 cases (69. 8%) and mixed infection in 19 cases (30. 2%) in 63 positive cases.
Mixed infection of staphylococcus aureus and B-hemolytic streptococcus were identified in 8 cases (42. 1%) whereas in 44 cases of single infection the pseudomonas aeruginosa was identified in 16 cases (36.4%).
3. The periodic observation of a variety of bacilli in 30 patients, staphylococcus aureus was identified 8 cases (26.7%) in postburn 5th day, 6 cases(20.0%) in postburn 7th day and only 3 cases (10. 0%) in 9th day.
It was observed that infection rate of staphylococcus aureus was gradually decreased but the rate of infection of pseudomonas aeruginosa showed a tendency of increasing.
Increase of pseudomonas aeruginosa was identifiedin only 2 cases (6.7%) out of 30 cases in postburn 5th day whereas it was found in 6 cases (20.0%) in postburn 7th day and n cases (36.7%) in postburn 9th day.
4. The identification rate of each kinds of bacillus, the gram-negative group was much more identified. The gram positive bacilli were identified in 36 strains(32.7%)and the gram negative bacilli in 47 strains (42.7%) out of 83 strains (75.4%).
Of 27 gram negative strains, pseudomonas aeruginosa was the most common, being identified in 19 strains (17. 3%) and escherichia coli in 17 strains (15.4%).
5. The identification rate on the base of he extent of burns16 cases (84.2%) of 19 cases of pseudomonas aeruginosa were identified in a total cases.
Next staphylococcus aureus was identified in 12 cases (70.6%) out of 17 cases.
6. Result of susceptibility to antibiotics was that staphylococcus aureus (10/25) and is hem-olytic streptococcus was the most susceptible to penicillin, pseudomonas aeruginosa to gentam-ycin (10/28), geopen (9/28) and cephoran (8J28) and E. coli to kanamycin (10/26).
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